• B. fragilis conjugation of GABA and tyramine to deoxycholic acid
    • Cover image artwork for Mullowney, M. W.; Fiebig, A.; Schnizlein, M. K.; McMillin, M.; Koval, J.; Rubin, D.; Dalal, S.; Sogin, M.L.; Chang, E. B.; Sidebottom, A. M.; Crosson, S. Microbially-catalyzed conjugation of GABA and tyramine to bile acids. J. Bacteriol. 2024,  206 , e00426–23.
  • WORLD RECORD INTACT MASS DETECTED BY MS COVER ART
    • Animated version of cover image artwork for McGee, J.P.; Melani, R.D.; Yip, P.F.; Senko, M.W.; Compton, P.D.; Kafader, J.O.;Kelleher, N.L. Isotopic Resolution of Protein Complexes up to 466 kDa Using Individual Ion Mass Spectrometry. Anal. Chem. 2020. 93, 2723-2727.
  • I2MS COVER ART
    • Cover image artwork (and table of contents graphic) for Kafader, J.O.; Durbin, K.R.; Melani, R.D.; Des Soye B.J.; Schachner, L.F.; Senko, M.W.; Compton, P.D.; Kelleher, N.L. Individual Ion Mass Spectrometry Enhances the Sensitivity and Sequence Coverage of Top Down Mass Spectrometry. J. Proteome Res. 2020, 19, 1346–1350.
  • BiG-SCAPE-CORASON COVER ART
    • Cover image artwork for Navarro-Muñoz, J.*; Selem-Mojica, N.*; Mullowney, M.W.*; Kautsar, S.; Tryon, J.H.; Parkinson, E.; Santos, E.D.L.; Yeong, M.; Cruz-Morales, P.; Abubucker, S.; Roeters, A.; Lokhorst, W.; Fernandez-Guerra, A.; Dias Cappelini, L.T.; Goering, A.W.; Thomson, R.J.; Metcalf, W.W.; Kelleher, N.L.; Barona-Gomez, F.; Medema, M.H. A computational framework to explore large-scale biosynthetic diversity. Nat. Chem. Biol. 2020, 16, 60–68.
      *co-first authors
  • a bacterial pimarane diterpene
    • Micromonospora sp. G039 cultured in the shape of the isopimara-2-one-3-ol-8,15-diene chemical structure. From: Mullowney, M.W.; Ó hAinmhire, E.; Tanouye, U.; Burdette, J.E.; Pham, V.C.; Murphy, B.T. A Pimarane Diterpene and Cytotoxic Angucyclines from a Marine-Derived Micromonospora sp. in Vietnam’s East Sea. Mar. Drugs. 2015, 13, 5815-27.
  • natural products from thioester reductase containing biosynthetic gene clusters COVER ART
    • Cover image artwork for Mullowney, M.W.; McClure, R.; Robey, M.; Kelleher, N.L..; Thomson, R.J. Natural products from biosynthetic assembly lines terminating in thioester reductases. Nat. Prod. Rep. 2018, 35, 847-78.
    A fractionated extract from fermentation of Streptomyces sp. F001, which contains diazaquinomycins A-F (red), and akashins (cyan). From: Mullowney, M.W.; Ó hAinmhire, E.; Shaikh, A.; Wei, X.; Tanouye, U.; Santarsiero, B.D.; Burdette, J.E.; Murphy, B.T. Diazaquinomycins E–G, novel diaza-anthracene analogs from a marine-derived Streptomyces sp. Mar. Drugs. 2014, 12, 3574-86.
    A fractionated extract from fermentation of Streptomyces sp. F001, which contains diazaquinomycins A-F (red), and akashins (cyan). From: Mullowney, M.W.; Ó hAinmhire, E.; Shaikh, A.; Wei, X.; Tanouye, U.; Santarsiero, B.D.; Burdette, J.E.; Murphy, B.T. Diazaquinomycins E–G, novel diaza-anthracene analogs from a marine-derived Streptomyces sp. Mar. Drugs. 2014, 12, 3574-86.
    A round-bottom flask containing the cyan-colored akashin class of natural products from Streptomyces sp. F001. From: Mullowney, M.W.; Ó hAinmhire, E.; Shaikh, A.; Wei, X.; Tanouye, U.; Santarsiero, B.D.; Burdette, J.E.; Murphy, B.T. Diazaquinomycins E–G, novel diaza-anthracene analogs from a marine-derived Streptomyces sp. Mar. Drugs. 2014, 12, 3574-86.
    Round-bottom flasks containing the bright red-colored diazaquinomycin class of natural products from Streptomyces sp. F001. From: Mullowney, M.W.; Ó hAinmhire, E.; Shaikh, A.; Wei, X.; Tanouye, U.; Santarsiero, B.D.; Burdette, J.E.; Murphy, B.T. Diazaquinomycins E–G, novel diaza-anthracene analogs from a marine-derived Streptomyces sp. Mar. Drugs. 2014, 12, 3574-86.
    Round-bottom flasks containing the bright red-colored diazaquinomycin class of natural products from Streptomyces sp. F001. From: Mullowney, M.W.; Ó hAinmhire, E.; Shaikh, A.; Wei, X.; Tanouye, U.; Santarsiero, B.D.; Burdette, J.E.; Murphy, B.T. Diazaquinomycins E–G, novel diaza-anthracene analogs from a marine-derived Streptomyces sp. Mar. Drugs. 2014, 12, 3574-86.